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Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in Rats

机译：在不同时间点施用阿魏酸可通过激活大鼠脑缺血再灌注亚急性期的p38 MAPK / p90RSK / CREB / Bcl-2抗凋亡信号来预防脑梗塞

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ObjectivesThis study aimed to evaluate the effects of ferulic acid (FA) administered at various time points before or after 30 min of middle cerebral artery occlusion (MCAo) followed by 7 d of reperfusion and to examine the involvement of mitogen-activated protein kinase (MAPK) signaling pathways in the cortical penumbra.

机译：目的本研究旨在评估在大脑中动脉闭塞（MCAo）30分钟前后再灌注7天之前或之后的各个时间点施用阿魏酸（FA）的效果，并检查有丝分裂原活化蛋白激酶（MAPK）的参与）在皮层半影中的信号通路。

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期刊名称 other
作者
Chin-Yi Cheng; Nou-Ying Tang; Shung-Te Kao; Ching-Liang Hsieh;
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年(卷),期 -1(11),5
年度 -1
页码 e0155748
总页数 20
原文格式 PDF
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入库时间 2022-08-21 11:12:31

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机译：Angelica Sinensis提取物通过激活P38 Mapk介导的P90RSK / P-BAD和P90RSK / CREB / BDNF信号传导在大鼠的瞬时全球脑缺血后，防止海马再灌注损伤
2. Ferulic acid ameliorates cerebral infarction by activating Akt/mTOR/4E-BP1/Bcl-2 anti-apoptotic signaling in the penumbral cortex following permanent cerebral ischemia in rats [J] . Cheng Chin-Yi, Kao Shung-Te, Lee Yu-Chen Nature reviews Cancer . 2019,第2期

机译：通过在大鼠永久性脑缺血之后激活Penumbral皮质中的Akt / mtor / 4e-bp1 / bcl-2抗凋亡信号来改善脑梗塞的脑梗死
3. Angelica sinensis Exerts Angiogenic and Anti-apoptotic Effects Against Cerebral Ischemia-Reperfusion Injury by Activating p38MAPK/HIF-1 alpha/VEGF-A Signaling in Rats [J] . Cheng Chin-Yi, Ho Tin-Yun, Hsiang Chien-Yun, The American journal of Chinese medicine . 2017,第8期

机译：Angelica Sinensis通过在大鼠中激活P38MAPK / HIF-1α/ VEGF-A信号来施加血管生成和抗凋亡作用对脑缺血再灌注损伤
4. Effects of gastrodin on amino acids after cerebral ischemia-reperfusion injury in rat striatum [C] . Xiaodong Bie, Yueqing Chen, Jin Han, 国际营养科学联盟第八届临床营养学大会暨第五届亚太临床营养学会大会 . 2006

机译：天麻素对大鼠纹状体脑缺血再灌注损伤后氨基酸的影响
5. Electroacupuncture at different frequencies (5Hz and 25Hz) ameliorates cerebral ischemia-reperfusion injury in rats: possible involvement of p38 MAPK-mediated anti-apoptotic signaling pathways [O] . Chin-Yi Cheng, Jaung-Geng Lin, Nou-Ying Tang, 2015

机译：不同频率（5Hz和25Hz）的电针改善大鼠脑缺血-再灌注损伤：可能涉及p38 MAPK介导的抗凋亡信号通路
6. Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in Rats. [O] . Chin-Yi Cheng, Nou-Ying Tang, Shung-Te Kao, 2016

机译：不同时间点阿魏酸通过激活p38 mapK / p90RsK / CREB / Bcl-2抗凋亡信号在大鼠脑缺血再灌注损伤的亚急性期保护脑梗死。

Ferulic Acid Administered at Various Time Points Protects against Cerebral Infarction by Activating p38 MAPK/p90RSK/CREB/Bcl-2 Anti-Apoptotic Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion Injury in Rats

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