Autism Spectrum and Psychosis Risk in the 22q11.2 Deletion Syndrome. Findings from a Prospective Longitudinal Study

摘要

BackgroundIndividuals with 22q11.2 deletion syndrome (22q11DS) have a 25% risk for schizophrenia and related psychotic disorders. Some have hypothesized that Autism Spectrum Disorders (ASD) diagnosed in children with 22q11DS may actually represent the social-communicative defects often observed during the early developmental stages of schizophrenia.