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Pharmacokinetic and pharmacodynamic modelling after subcutaneous intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats

机译：皮下静脉和颊部给予高浓度丁丙诺啡制剂在有意识的猫中的药代动力学和药效学模型

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摘要

BackgroundThe aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol^™) in cats.

机译：背景：本研究的目的是描述联合药代动力学-药效学模型并评估高浓度丁丙诺啡（Simbadol ^{™）在猫中的热镇痛作用。}

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期刊名称 other
作者
Graeme M. Doodnaught; Beatriz P. Monteiro; Javier Benito; Daniel Edge; Francis Beaudry; Ludovic Pelligand; Paulo Steagall;
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年(卷),期 -1(12),4
年度 -1
页码 e0176443
总页数 16
原文格式 PDF
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专利

1. Pharmacokinetic and pharmacodynamic modelling of intravenous, intramuscular and subcutaneous buprenorphine in conscious cats. [J] . Steagall P. V. M., Pelligand L., Giordano T., Veterinary Anaesthesia and Analgesia . 2013,第1期

机译：在有意识的猫中，静脉，肌肉和皮下注射丁丙诺啡的药代动力学和药效学模型。
2. Thermal antinociception after buccal administration of a high-concentration formulation of buprenorphine (Simbadol) at 0.24 mg kg(-1) in conscious cats [J] . Doodnaught Graeme M., Monteiro Beatriz, Edge Daniel, Veterinary Anaesthesia and Analgesia . 2018,第5期

机译：在有意识的猫体中以0.24mg kg（-1）的丁丙诺啡（Simbadol）高浓度制剂施用热抗血液促进剂
3. Pharmacokinetic and pharmacodynamic evaluation of high doses of buprenorphine delivered via high-concentration formulations in cats [J] . Taylor Polly M., Luangdilok Carmela H., Sear John W. Journal of feline medicine and surgery . 2016,第4期

机译：通过高浓度制剂在猫中高剂量丁丙诺啡的药代动力学和药效学评估
4. PHARMACOKINETICS OF INTRAVENOUS AND SUBCUTANEOUS DOLASETRON AND PHARMACODYNAMICS OF SUBCUTANEOUS DOLASETRON IN PURPOSE-BRED CATS [C] . Andrea Herndon, Liberty Sieberg, Leigh Davis, Conference of the American^College^of^Veterinary^Internal^Medicine . 2016

机译：静脉和皮下Dolasetron的药代动力学和皮下Dolasetron在目的繁殖的猫中的药效学
5. Pharmacokinetics and pharmacodynamics of buprenorphine and norbuprenorphine and the identification of norbuprenorphine metabolites. [D] . Tegegne, Gennet. 2006

机译：丁丙诺啡和去甲丁丙诺啡的药代动力学和药效学以及去甲丁丙诺啡代谢物的鉴定。
6. Pharmacokinetics (PK) pharmacodynamics (PD) and PK-PD integration of ceftiofur after a single intravenous subcutaneous and subcutaneous-LA administration in lactating goats [O] . Emilio Fernández-Varón, Carlos Cárceles-García, Juan Manuel Serrano-Rodríguez, 2016

机译：哺乳山羊单次静脉内皮下和皮下LA给药后头孢噻呋的药代动力学（PK）药效学（PD）和PK-PD整合
7. Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats. [O] . Graeme M Doodnaught, Beatriz P Monteiro, Javier Benito, 2017

机译：在有意识的猫中皮下，静脉内和口腔给药高浓度丁丙诺啡制剂后的药代动力学和药效学模型。
8. Use Of Colistin Serum Concentrations After Intravenous Administration Of Colistimethate Sodium To Determine Pharmacokinetic And Pharmacodynamic Relationships [R] . Byers, D. 2011

机译：静脉注射Colistimethate钠后使用粘菌素血清浓度来确定药代动力学和药效学关系

Pharmacokinetic and pharmacodynamic modelling after subcutaneous intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats

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