PHARMACOKINETICS OF INTRAVENOUS AND SUBCUTANEOUS DOLASETRON AND PHARMACODYNAMICS OF SUBCUTANEOUS DOLASETRON IN PURPOSE-BRED CATS

摘要

Dolasetron is a 5-HT3 receptor antagonist anti-emetic and is typically dosed at 0.5-1 mg/kg IV or SQ once daily. Pharmacokinetic (PK) and pharmacodynamic (PD) studies in cats have not been previously performed. The purpose of this study was to evaluate these parameters in purpose-bred cats.