Joint effect of maternal plasma homocysteine and prepregnancy obesity on child blood pressure: A prospective birth cohort study

摘要

Background/ObjectivesElevated homocysteine (Hcy) is a known cardiovascular risk factor. However, its role in intergenerational cardiometabolic risk is unknown. We hypothesized that maternal elevated Hcy can act alone or in combination with maternal prepregnancy obesity to increase child systolic blood pressure (SBP).