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Nanotechnology in agriculture: Opportunities toxicological implications and occupational risks

机译:农业纳米技术:机会毒理学意义和职业风险

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摘要

Nanotechnology has the potential to make a beneficial impact on several agricultural, forestry, and environmental challenges, such as urbanization, energy constraints, and sustainable use of resources. However, new environmental and human health hazards may emerge from nano-enhanced applications. This raises concerns for agricultural workers who may become primarily exposed to such xenobiotics during their job tasks. The aim of this review is to discuss promising solutions that nanotechnology may provide in agricultural activities, with a specific focus on critical aspects, challenging issues, and research needs for occupational risk assessment and management in this emerging field. Eco-toxicological aspects were not the focus of the review. Nano-fertilizers, (nano-sized nutrients, nano-coated fertilizers, or engineered metal-oxide or carbon-based nanomaterials per se), and nano-pesticides, (nano-formulations of traditional active ingredients or inorganic nanomaterials), may provide a targeted/controlled release of agrochemicals, aimed to obtain their fullest biological efficacy without overdosage. Nano-sensors and nano-remediation methods may detect and remove environmental contaminants. However, limited knowledge concerning nanomaterial biosafety, adverse effects, fate, and acquired biological reactivity once dispersed into the environment, requires further scientific efforts to assess possible nano-agricultural risks. In this perspective, toxicological research should be aimed to define nanomaterial hazards and levels of exposure along the life-cycle of nano-enabled products, and to assess those physico-chemical features affecting nanomaterial toxicity, possible interactions with agro-system co-formulants, and stressors. Overall, this review highlights the importance to define adequate risk management strategies for workers, occupational safety practices and policies, as well as to develop a responsible regulatory consensus on nanotechnology in agriculture.
机译:纳米技术有可能对一些农业,林业和环境挑战产生有益的影响,例如城市化,能源限制和资源的可持续利用。但是,纳米增强的应用可能会出现新的环境和人类健康危害。这引起了农业工人的关注,他们可能在工作中主要暴露于这种异生物素。这篇综述的目的是讨论纳米技术可以在农业活动中提供的有前途的解决方案,特别关注关键方面,具有挑战性的问题以及该新兴领域中职业风险评估和管理的研究需求。生态毒理学方面不是审查的重点。纳米肥料(纳米级营养素,纳米涂层肥料或工程金属氧化物或碳基纳米材料本身)和纳米农药(传统活性成分或无机纳米材料的纳米配方)可以提供农药的靶向/控释,旨在获得其最大的生物学功效而又不过量。纳米传感器和纳米补救方法​​可以检测和去除环境污染物。但是,有关纳米材料生物安全性,不良影响,命运以及一旦分散到环境中后获得的生物反应性的知识有限,需要进一步的科学努力来评估可能的纳米农业风险。从这个角度出发,毒理学研究应旨在界定纳米材料的危害和沿纳米产品生命周期的暴露水平,并评估影响纳米材料毒性的那些理化特征,与农业系统共制剂的可能相互作用,和压力源。总体而言,本次审查强调了为工人定义适当的风险管理策略,职业安全实践和政策以及在农业纳米技术上形成负责任的监管共识的重要性。

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