WHICH PHYSICAL EXERCISES IMPROVE COGNITION IN MCI? LESSONS LEARNED FROM THE PROMOTE TRIAL

摘要

Exercise is a promising strategy for the promotion of cognitive and brain health. However, whether it can still benefit for those who have already exhibit cognitive deficits is not well established. Moreover, there are two types of exercise: 1) aerobic training (AT); and 2) resistance training (RT; e.g., lifting weights). Evidence from randomized controlled trials (RCTs) suggests that both AT and RT enhance cognitive function in healthy older adults; although there has been extensive focus on AT. Thus, more research is needed on ascertaining the efficacy of both AT and RT among those at risk for dementia, such as those with mild cognitive impairment (MCI). We will summarize results from RCT of exercise in older adults with MCI, with a specific focus on the results of a 6-month RCT of AT and RT.