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Safety and Efficacy of Teduglutide (Gattex) in patients with Crohn’s disease and need for parenteral support due to short bowel syndrome associated intestinal failure

机译：特德鲁肽（Gattex）在克罗恩病患者中的安全性和有效性并且由于肠功能不全伴有肠功能衰竭而需要肠胃外支持

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摘要

BackgroundTeduglutide is a GLP-2 analogue indicated for treatment of adults with short bowel syndrome (SBS). Due to the rarity of SBS, real-world safety or efficacy data are not available in patients with Crohn’s disease (CD) and SBS treated with teduglutide.

机译：背景Teduglutide是一种GLP-2类似物，适用于治疗患有短肠综合征（SBS）的成年人。由于SBS的稀有性，因此在克罗恩病（CD）和接受teduglutide治疗的SBS患者中，无法获得真实的安全性或疗效数据。

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期刊名称 other
作者
Bharati Kochar; Millie D. Long; Edward Shelton; Lorraine Young; Francis A. Farraye; Vijay Yajnik; Hans Herfarth;
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作者单位

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年(卷),期 -1(51),6
年度 -1
页码 508–511
总页数 10
原文格式 PDF
正文语种
中图分类
关键词
Crohn’s Disease Short Bowel Syndrome Parenteral Nutrition Teduglutide Immunosuppression;

机译：克罗恩病;短肠综合症;肠胃外营养;特度鲁肽;免疫抑制;

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1. Safety and Efficacy of Teduglutide (Gattex) in Patients With Crohn's Disease and Need for Parenteral Support Due to Short Bowel Syndrome-associated Intestinal Failure [J] . Kochar Bharati, Long Millie D., Shelton Edward, Journal of clinical gastroenterology . 2017 ,第6期

机译：Teduglutide（Gattex）在克罗恩病患者中的安全性和有效性，并且由于短肠综合征相关肠道衰竭而需要肠胃外支持
2. Reduction of Parenteral Nutrition and Hydration Support and Safety With Long‐Term Teduglutide Treatment in Patients With Short Bowel Syndrome?Associated Intestinal Failure: STEPS‐3 Study [J] . Douglas L. Seidner, Ken Fujioka, Joseph I. Boullata, Nutrition in clinical practice : . 2018 ,第4期

机译：长期特度鲁肽治疗短期肠综合征相关肠衰竭的肠胃营养，水合作用和安全性降低：STEPs-3研究
3. Reduction of Parenteral Nutrition and Hydration Support and Safety With Long‐Term Teduglutide Treatment in Patients With Short Bowel Syndrome?Associated Intestinal Failure: STEPS‐3 Study [J] . Seidner Douglas L., Fujioka Ken, Boullata Joseph I., Nutrition in clinical practice: official publication of the American Society for Parenteral and Enteral Nutrition . 2018 ,第4期

机译：短期综合征患者的长期促德金蛋白酶治疗肠外营养和水化载体和安全性的减少？相关肠道衰竭：步骤-3研究
4. Avoiding Parenteral Nutrition associated Cholestasis in Short Bowel Syndrome might reduce the need of a combined hepatic-bowel transplantation [C] . Corasaniti L., Righetti L., Boroni G., International Small Bowel Transplant Symposium . 2009

机译：避免在短肠综合征中肠外营养相关的胆汁淤积可能会降低组合肝肠进肠移植的需要
5. Quantifying disease progression trajectory and investigating the impact of early initiation of biologic therapy in patients with Crohn's disease using the Lemann index of cumulative bowel damage. [D] . Panchal, Hina J. 2017

机译：使用累积肠损伤的Lemann指数量化疾病进展轨迹，并研究早期开始生物治疗对克罗恩病患者的影响。
6. Independence From Parenteral Nutrition and Intravenous Fluid Support During Treatment With Teduglutide Among Patients With Intestinal Failure Associated With Short Bowel Syndrome [O] . Kishore R. Iyer, Marek Kunecki, Joseph I. Boullata, -1

机译：短肠综合征合并肠衰竭的患者在接受泰德鲁肽治疗期间独立于肠外营养和静脉输液
7. Safety and Efficacy of Teduglutide (Gattex) in Patients With Crohn’s Disease and Need for Parenteral Support Due to Short Bowel Syndrome–associated Intestinal Failure [O] . Bharati Kochar, Millie D. Long, Edward Shelton, 2017

机译：Teduglutide（Gattex）在克罗恩病患者中的安全性和有效性，并且由于短肠综合征相关肠道衰竭而需要肠胃外促进

Safety and Efficacy of Teduglutide (Gattex) in patients with Crohn’s disease and need for parenteral support due to short bowel syndrome associated intestinal failure

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