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Inhibitory effects of total saponin from Korean Red Ginseng on Ca2+i mobilization through phosphorylation of cyclic adenosine monophosphate-dependent protein kinase catalytic subunit and inositol 145-trisphosphate receptor type I in human platelets

机译：大红参总皂苷通过环磷酸腺苷依赖性蛋白激酶催化亚基和肌醇I145-三磷酸受体I型磷酸化对Ca2 + i动员的抑制作用

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BackgroundIntracellular Ca²⁺([Ca²⁺]i) is a platelet aggregation-inducing molecule. Therefore, understanding the inhibitory mechanism of [Ca²⁺]i mobilization is very important to evaluate the antiplatelet effect of a substance. This study was carried out to understand the Ca²⁺-antagonistic effect of total saponin from Korean Red Ginseng (KRG-TS).

机译：背景细胞内Ca ^{2 + （[Ca ^{2 + ] i）是诱导血小板聚集的分子。因此，了解[Ca ^{2 + ] i动员的抑制机制对于评估物质的抗血小板作用非常重要。进行本研究以了解韩国红参总皂苷（KRG-TS）的Ca ^{2 + 拮抗作用。}}}}

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期刊名称 Journal of Ginseng Research
作者
Jung-Hae Shin; Hyuk-Woo Kwon; Hyun-Jeong Cho; Man Hee Rhee; Hwa-Jin Park;
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作者单位

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年(卷),期 2015(39),4
年度 2015
页码 354–364
总页数 11
原文格式 PDF
正文语种
中图分类
关键词
Casup2+/sup-mobilization inositol 145-trisphosphate receptor type I (Sersup1756/sup) phosphorylation Panax ginseng protein kinase A catalytic subunit (Thrsup197/sup) phosphorylation total saponin from Korean Red Ginseng;

机译：Ca sup 2 + / sup动员;I型肌醇145-三磷酸受体（Ser sup 1756 / sup）磷酸化;人参;蛋白激酶A催化亚基（Thr sup 197 / sup）磷酸化;来自韩国红参的总皂苷;

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1. Inhibitory effects of total saponin from Korean Red Ginseng on [Ca2+]i mobilization through phosphorylation of cyclic adenosine monophosphate-dependent protein kinase catalytic subunit and inositol 1,4,5-trisphosphate receptor type I in human platelets [J] . Jung-Hae Shin, Hyuk-Woo Kwon, Hyun-Jeong Cho, Journal of Ginseng Research . 2015,第4期

机译：大红参总皂苷对人血小板中环磷酸腺苷依赖性蛋白激酶催化亚基和肌醇1,4,5-三磷酸受体I型磷酸化的[Ca2 +] i动员的抑制作用
2. SPECIFIC PHOSPHORYLATION OF A SITE IN THE FULL-LENGTH FORM OF THE ALPHA-1 SUBUNIT OF THE CARDIAC L-TYPE CALCIUM CHANNEL BY ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE-DEPENDENT PROTEIN KINASE [J] . Dejongh KS, Murphy BJ, Colvin AA, Biochemistry . 1996,第32期

机译：腺嘌呤3'，5'-单磷酸依赖的蛋白激酶对心脏L型钙通道Alpha-1亚基的全长形式的特定磷酸化
3. Identification of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase phosphorylation site in the carboxy terminal tail of human D1 dopamine receptor. [J] . Zamanillo D, Casanova E, Alonso Llamazares A, Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 1995,第3期

机译：鉴定人D1多巴胺受体羧基末端尾部的环状腺苷3'，5'-单磷酸依赖性蛋白激酶磷酸化位点。
4. Antiserum against the catalytic subunit of adenosine 3:5-cyclic monophosphate-dependent protein kinase. Reactivity towards various protein kinases. [O] . G Schwoch, A Hamann, H Hilz 1980

机译：抗腺苷3：5-环一磷酸依赖蛋白激酶催化亚基的抗血清。对各种蛋白激酶的反应性。
5. Inhibitory effects of total saponin from Korean Red Ginseng on Ca2+i mobilization through phosphorylation of cyclic adenosine monophosphate-dependent protein kinase catalytic subunit and inositol 1,4,5-trisphosphate receptor type I in human platelets [O] . Shin Jung-Hae, Kwon Hyuk-Woo, Cho Hyun-Jeong, 2015

机译：大红参总皂苷对人血小板中环磷酸腺苷依赖性蛋白激酶催化亚基和肌醇1,4,5-三磷酸受体I型磷酸化的Ca2 + i动员的抑制作用

Inhibitory effects of total saponin from Korean Red Ginseng on Ca2+i mobilization through phosphorylation of cyclic adenosine monophosphate-dependent protein kinase catalytic subunit and inositol 145-trisphosphate receptor type I in human platelets

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