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Evaluation of Transcatheter Heart Valve Biomaterials: Biomechanical Characterization of Bovine and Porcine Pericardium

机译:经导管心脏瓣膜生物材料的评估:牛和猪心包的生物力学表征

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摘要

ObjectiveBovine pericardium (BP) has been identified as a choice biomaterial for the development of surgical bioprosthetic heart valves (BHV) and transcatheter aortic valves (TAV). Porcine pericardium (PP) and younger BP have been suggested as candidates TAV leaflet biomaterials for smaller-profile devices due to their reduced thickness; however, their mechanical and structural properties remain to be fully characterized. This study characterized the material properties of chemically treated thick (PPK) and thin (PPN) PP, as well as fetal (FBP), calf (CBP) and adult (ABP) BP tissues in order to better understand their mechanical behavior.
机译:目的牛心包(BP)已被确定为开发外科生物人工心脏瓣膜(BHV)和经导管主动脉瓣膜(TAV)的生物材料。猪心包(PP)和较年轻的BP由于厚度减小,已被建议用作较小型设备的TAV小叶生物材料。但是,它们的机械和结构性能仍有待充分表征。这项研究表征了化学处理过的厚(PPK)和薄(PPN)PP以及胎儿(FBP),小腿(CBP)和成人(ABP)BP组织的材料特性,以便更好地了解其机械行为。

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