Comparison of the Cepheid GeneXpert CT/NG Assay to the Hologic Aptima Combo 2 Assay for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in self-collected rectal swabs

摘要

Self-collected rectal-swabs were tested for CT and NG on GeneXpert CT/NG as compared to APTIMA Combo2. Of 448 rectal-swabs, 22 were positive for CT; 7 for NG on both assays; two were discordant. Sensitivity and specificity of GeneXpert was 95.5% and 99.7% for chlamydia, respectively; for gonorrhea both were 100%.