S100β in Newborns after C-Section with General versus Epidural Anesthesia: a prospective observational study

摘要

BackgroundPreclinical evidence suggests that general anesthetics can dose-dependently induce neurodegeneration in the developing brains of animals which can be reliably determined by measurement of blood S100β, but this correlation remains unclear in humans. We hypothesized that S100β would not be increased in cord arterial blood of fetuses exposed briefly to general anesthetics during a C-section, compared to epidural anesthesia.