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Novel biomarker-based model for the prediction of sorafenib response and overall survival in advanced hepatocellular carcinoma: a prospective cohort study

机译：基于新型生物标志物的索拉非尼反应和总生存期预测模型在前瞻性队列研究中的应用

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BackgroundPrediction of the outcome of sorafenib therapy using biomarkers is an unmet clinical need in patients with advanced hepatocellular carcinoma (HCC). The aim was to develop and validate a biomarker-based model for predicting sorafenib response and overall survival (OS).

机译：背景技术使用生物标志物预测索拉非尼治疗的结果是晚期肝细胞癌（HCC）患者尚未满足的临床需求。目的是开发和验证基于生物标志物的模型，以预测索拉非尼反应和总生存期（OS）。

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期刊名称 BMC Cancer
作者
Hwi Young Kim; Dong Hyeon Lee; Jeong-Hoon Lee; Young Youn Cho; Eun Ju Cho; Su Jong Yu; Yoon Jun Kim; Jung-Hwan Yoon;
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作者单位

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年(卷),期 2018(18),-1
年度 2018
页码 307
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学 ;
关键词
Hepatocellular carcinoma Sorafenib Response Biomarker Prediction;

机译：肝细胞癌;索拉非尼;反应;生物标志物;预测;

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专利

1. Novel biomarker-based model for the prediction of sorafenib response and overall survival in advanced hepatocellular carcinoma: a prospective cohort study [J] . Hwi Young Kim, Dong Hyeon Lee, Jeong-Hoon Lee, BMC Cancer . 2018 ,第1期

机译：基于新型生物标志物的索拉非尼响应预测和先进肝细胞癌整体生存的模型：展望队列研究
2. A Novel Biomarker-Based Model for the Prediction of Response to Sorafenib and Overall Survival for Advanced Hepatocellular Carcinoma: A Prospective Cohort Study [J] . Kim Hwi Young, Lee Dong Hyeon, Cho Eun Ju, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2016 ,第S1期

机译：基于生物标志物的基于生物标志物的模型，用于预测索拉非尼和晚期肝细胞癌的整体存活：一项潜在的队列研究
3. Comparable effects of Jiedu Granule, a compound Chinese herbal medicine, and sorafenib for advanced hepatocellular carcinoma: A prospective multicenter cohort study [J] . Analysis and applications . 2020 ,第4期

机译：Jiedu颗粒，复合中草药和索拉芬皮治疗晚期肝细胞癌的可比效果：一项潜在的多中心队列研究
4. Photoacoustic-ultrasonic imaging biomarkers for treatment-response assessment of sorafenib in a rat model of hepatocellular carcinoma [C] . Houra Taghavi, Nina Munoz, Mohamed Naser, IEEE International Ultrasonics Symposium . 2017

机译：光声-超声成像生物标记物用于索拉非尼在肝细胞癌大鼠模型中的治疗反应评估
5. Poly(lactide-co-glycolide) Microspheres for Localized, Magnetic Resonance Imaging Monitored, Transcatheter Delivery of Sorafenib to Hepatocellular Carcinoma. [D] . Chen, Jeane. 2015

机译：聚（丙交酯-共-乙交酯）微球体用于局部监测，磁共振成像监测，索拉非尼经导管输送至肝细胞癌。
6. Sorafenib with Transarterial Chemoembolization Achieves Improved Survival vs. Sorafenib Alone in Advanced Hepatocellular Carcinoma: A Nationwide Population-Based Cohort Study [O] . Victor C. Kok, Yu-Ching Chen, Yang-Yuan Chen, 2019

机译：索拉非尼与经动脉化学栓塞术相比晚期肝细胞癌中单独使用索拉非尼可提高生存率：一项基于全国人群的队列研究
7. The impact of combining Selective Internal Radiation Therapy (SIRT) with sorafenib on overall survival in patients with advanced hepatocellular carcinoma: The SORAMIC trial palliative cohort [O] . J. Ricke, B. Sangro, H. Amthauer, 2018

机译：将选择性内部放射治疗（SIRT）与Sorafenib对先进肝细胞癌患者总生存的影响：索拉斯审判姑息队

Novel biomarker-based model for the prediction of sorafenib response and overall survival in advanced hepatocellular carcinoma: a prospective cohort study

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