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Design and implementation of pragmatic clinical trials using the electronic medical record and an adaptive design

机译：使用电子病历和自适应设计的实用临床试验的设计和实现

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摘要

Objectives:To demonstrate the feasibility of pragmatic clinical trials comparing the effectiveness of treatments using the electronic medical record (EMR) and an adaptive assignment design.

机译：目的：通过比较实用的电子病历（EMR）和适应性作业设计，论证比较实用的临床试验的可行性。

著录项

期刊名称 JAMIA Open
作者
Kelly Claire Simon; Samuel Tideman; Laura Hillman; Rebekah Lai; Raman Jathar; Yuan Ji; Stuart Bergman-Bock; James Castle; Tiffani Franada; Thomas Freedom; Revital Marcus; Angela Mark; Steven Meyers; Susan Rubin; Irene Semenov; Chad Yucus; Anna Pham; Lisette Garduno; Monika Szela; Roberta Frigerio; Demetrius M. Maraganore;
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年(卷),期 2018(1),1
年度 2018
页码 99–106
总页数 15
原文格式 PDF
正文语种
中图分类
关键词
pragmatic clinical trials precision medicine clinical decision support electronic medical records sub-group based adaptive designs;

机译：实用临床试验;精准医学;临床决策支持;电子病历;基于分组的自适应设计;
入库时间 2022-08-21 11:07:16

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专利

1. A Pragmatic Cluster Randomized Trial of an Electronic Clinical Decision Support System to Improve Chronic Kidney Disease Management in Primary Care: Design, Rationale, and Implementation Experience [J] . Elaine C Khoong, Leah Karliner, Lowell Lo, JMIR Research Protocols . 2019,第6期

机译：电子临床决策支持系统的实用集群随机试验，用于改善初级保健中的慢性肾脏病管理：设计，原理和实施经验
2. Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy – the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial [J] . Kevin J. Anstrom, For the CleanUP-IPF Study Team, Imre Noth, Respiratory Research . 2020,第1期

机译：抗菌治疗的多中心，务实，开放式随机试验的设计和理由 - 使用务实设计术语特性肺纤维化术语（清除IPF）临床试验研究抗菌治疗策略临床疗效研究
3. Design and implementation of decision support for tobacco dependence treatment in an inpatient electronic medical record: a randomized trial [J] . Bernstein Steven L., Rosner June, DeWitt Michelle, Translational behavioral medicine. . 2017,第2期

机译：在住院电子病历中烟草依赖处理决策支持的设计与实现：随机试验
4. Clinical trials of an electronic medical record system [C] . Kitney, R.I., Bickram, . 1998

机译：电子病历系统的临床试验
5. Design of Adaptive Multiarm Multistage Clinical Trials [D] . Ghosh, Pranab. 2018

机译：自适应多臂多阶段临床试验的设计
6. Design and implementation of decision support for tobacco dependence treatment in an inpatient electronic medical record: a randomized trial [O] . Steven L. Bernstein, June Rosner, Michelle DeWitt, 2017

机译：住院电子病历中烟草依赖治疗决策支持的设计和实施：一项随机试验
7. Design and implementation of pragmatic clinical trials using the electronic medical record and an adaptive design [O] . Kelly Claire Simon, Samuel Tideman, Laura Hillman, 2018

机译：用电子医疗记录和自适应设计设计与实施务语临床试验

Design and implementation of pragmatic clinical trials using the electronic medical record and an adaptive design

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