Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use

摘要

Background & Aims:Neutrophil extracellular traps (NETs) are an important strategy utilized by neutrophils to immobilize and kill invading microorganisms. Here we studied NET formation and its clearance by macrophages (MØ) (efferocytosis) in acute sepsis following binge drinking.