RELATIONSHIP BETWEEN COGNITIVE FUNCTION AND PHYSICAL ACTIVITY USING NOVEL ACCELEROMETRY DERIVED METRICS

摘要

Given conflicting evidence, the relationship between cognitive function (CF) and physical activity (PA) remains unclear. We investigated the association between standardized cognitive scores for: memory, language, executive functioning, attention, and visuospatial processing, and three accelerometer-based PA metrics: total volume of daily activity on the log scale (TLAC), total daily activity counts (TAC), log total daily activity count (LTAC), and activity fragmentation (AF) among 714 BLSA participants aged > 50 years (49.6% men, age: 71.88 ± 9.99). In multivariable regression models adjusted for age, gender, and years of education, there was no association between executive function and any of the mtrics (p>0.05 for all). Language was associated with all four metrics, memory and visuospatial scores with AF and TLAC, and attention with LTAC, TAC and AF (p<0.05 for all). Results suggest that novel PA metrics capture aspects of PA that may be important for preserving CF. Findings should be confirmed using longitudinal data.