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Successful Implementation of a Shared Medical Appointment Model for Hepatitis C Treatment at a Community Health Center

机译:在社区卫生中心成功实施丙型肝炎治疗的共享医疗预约模式

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摘要

Highly efficacious direct acting antiviral (DAA) therapy for treatment of Hepatitis C Virus (HCV) infection is largely inaccessible to communities facing a shortage of available specialist providers. Though less demanding than previous interferon regimens, DAA therapy requires patients to adhere to 8–12 weeks of daily treatment, which can be challenging for some patient populations. Duffy Health Center, located on Cape Cod, Massachusetts, provides integrated medical, mental health and case management services to people who are homeless or at risk for homelessness. The goal of this manuscript is to evaluate the outcomes of treatment of HCV infection with a shared medical appointment (SMA) model. The primary outcome was sustained virologic response (SVR-12), or HCV RNA ≤ 15 IU/mL at 12 weeks post-treatment. There were 102 patients recruited, with a total of 104 treatments administered. Over three-fourths of patients who attended one SMA visit (78 of 102) continued in SMA for the duration of treatment. Of these patients opting for SMA, 99% (77 of 78) completed the full treatment course, and 91% (71 of 78) of SMA patients achieved SVR-12. DAA therapy provided by non-specialist providers using the SMA model yielded comparable response rates to those achieved by specialist providers, and has the potential to substantially increase access to HCV treatment for patient populations within high-risk communities.
机译:面对缺少专业医生的社区,很大程度上无法获得用于治疗丙型肝炎病毒(HCV)感染的高效直接作用抗病毒(DAA)治疗。尽管与以前的干扰素治疗相比,DAA治疗的要求不高,但它要求患者坚持每天8-12周的每日治疗,这对某些患者群体可能是一个挑战。位于马萨诸塞州科德角的达菲健康中心为无家可归或有无家可归风险的人们提供综合的医疗,心理健康和病例管理服务。本手稿的目的是通过共享医疗预约(SMA)模型评估HCV感染的治疗效果。主要结果是治疗后12周持续的病毒学应答(SVR-12)或HCV RNA≤15 IU / mL。招募了102位患者,总共进行了104种治疗。超过四分之三的患者接受过一次SMA访视(102人中有78人)在治疗期间继续接受SMA。这些选择SMA的患者中,有99%(78个中的77个)完成了整个治疗过程,而91%(78个中的71个)的SMA患者达到了SVR-12。非专家提供者使用SMA模型提供的DAA疗法可产生与专家提供者相当的响应率,并且有可能大幅增加高风险社区患者人群获得HCV治疗的机会。

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