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The Modality Effect on Delayed Free Recall in Non-demented Patients With Mild Parkinson’s Disease Progression

机译:轻度帕金森病进展的非痴呆患者延迟自由回忆的情态效应

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摘要

>Background: The modality effect plays the central role in learning and memory functions. Retrieval failure constitutes a common memory impairment that occurs among patients with Parkinson’s disease (PD). However, little knowledge exists about the relation between modality effect and delayed recall impairment in PD. The primary goal of this study was to compare delayed free recall performance between three different memory modalities (verbal, visual, and cross visual-verbal) in a sample of non-demented patients with mild PD progression. The secondary goal was to explore the frequency of deficient performance on the basis of normative comparisons on each of the three delayed free-recall measures.>Method: A total of 71 non-demented patients with mild PD progression were recruited for the administration of the Montreal Cognitive Assessment (MoCA), the Rey Auditory Verbal Learning Test (RAVLT), the Rey Osterrieth Complex Figure Test (ROCFT), and the Greek Version of Face-Name Associative Memory Examination (GR-FNAME12).>Results: The percentages of deficient-performances for the three delayed free recall measures were 45.1% (32/71), 39.4% (28/71) and 31% (22/71) for the GR-FNAME12, ROFCT and RAVLT, respectively. The results indicated no significant difference between performances of the GR-FNAME12 and ROCFT, both of which were significantly lower than performance on the RAVLT.>Conclusions: In conclusion, delayed free recall appears to be more severely affected in the cross visual-verbal and visual memory modalities than in verbal-memory modalities in the early phase of PD progression.
机译:>背景:情态效应在学习和记忆功能中起着核心作用。检索失败是帕金森病(PD)患者中常见的记忆障碍。然而,关于PD中的情态效应与延迟召回障碍之间关系的知识很少。这项研究的主要目的是比较样本量轻度无进展的非痴呆患者的三种不同记忆方式(语言,视觉和视觉交叉)之间的延迟自由回忆表现。次要目标是在三种延迟的自由召回措施的每一项的规范比较的基础上,探索表现不佳的频率。>方法:总共71例轻度PD进展的非痴呆患者招募来管理蒙特利尔认知评估(MoCA),雷伊听觉语言学习测验(RAVLT),雷伊Osterrieth复杂图形测验(ROCFT)和希腊语版的人名联想记忆测验(GR-FNAME12)。 >结果:三项延迟免费召回措施的绩效欠佳百分比分别为GR-45.1%(32/71),39.4%(28/71)和31%(22/71) FNAME12,ROFCT和RAVLT。结果表明GR-FNAME12和ROCFT的性能之间没有显着差异,两者均显着低于RAVLT的性能。>结论:总的来说,延迟的自由召回似乎对RAVLT的影响更大。在PD进展的早期阶段,视觉和语言的交叉记忆方式比语言记忆的方式要多。

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