Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions

机译：咪达唑仑在小儿严重疟疾和惊厥中的药代动力学和临床疗效

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摘要

AIMTo investigate the pharmacokinetics and clinical efficacy of intravenous (IV), intramuscular (IM) and buccal midazolam (MDZ) in children with severe falciparum malaria and convulsions.

机译：目的探讨严重恶性疟疾和惊厥患儿的静脉（IV），肌内（IM）和颊咪达唑仑（MDZ）的药代动力学和临床疗效。

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期刊名称 British Journal of Clinical Pharmacology
作者
Simon N Muchohi; Gilbert O Kokwaro; Bernhards R Ogutu; Geoffrey Edwards; Steve A Ward; Charles R J C Newton;
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作者单位

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年(卷),期 2008(66),4
年度 2008
页码 529–538
总页数 10
原文格式 PDF
正文语种
中图分类药学;
关键词
children convulsions malaria midazolam pharmacokinetics;

机译：儿童;惊厥;疟疾;咪达唑仑;药代动力学;

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专利

1. Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions. [J] . Muchohi SN, Kokwaro GO, Ogutu BR, British Journal of Clinical Pharmacology . 2008,第4期

机译：咪达唑仑在患有严重疟疾和惊厥的儿童中的药代动力学和临床疗效。
2. Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions. [J] . Muchohi SN, Obiero K, Newton CR, British Journal of Clinical Pharmacology . 2008,第1期

机译：劳拉西m在患有严重疟疾和惊厥的儿童中的药代动力学和临床疗效。
3. Pharmacokinetics and clinical effect of phenobarbital in children with severe falciparum malaria and convulsions. [J] . Kokwaro GO, Ogutu BR, Muchohi SN, British Journal of Clinical Pharmacology . 2003,第4期

机译：苯巴比妥对严重恶性疟疾和惊厥患儿的药代动力学和临床效果。
4. Severe malaria in children at Tsevie hospital (Togo) [C] . K. E. Djadou, E O Takassi, J K Guédénon, International Rural and Elderly Health Informatics Conference . 2017

机译：Tsevie医院（多哥）儿童中的严重疟疾
5. Biomarkers of severe malaria: Complement activation and dysregulated angiogenesis in placental malaria and cerebral malaria [D] . Conroy, Andrea 2011

机译：严重疟疾的生物标志物：胎盘疟疾和脑疟疾中的补体激活和血管生成失调
6. Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions [O] . Simon N Muchohi, Kenneth Obiero, Charles R J C Newton, 2008

机译：劳拉西m在严重疟疾和惊厥患儿中的药代动力学和临床疗效
7. Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions. [O] . Muchohi, SN, Kokwaro, GO, Ogutu, BR, 2008

机译：咪达唑仑在患有严重疟疾和惊厥的儿童中的药代动力学和临床疗效。
8. Efficacy and Pharmacokinetic Evaluation of a Dose of Diazepam That Will Reducethe Incidence of Convulsions in Indian Rhesus Monkeys Pretreated with Pyridostigmine Bromide, Challenged with Soman, and Treated with Atropine and Pralidoxime Chloride with the [R] . Olson, C. T., Dill, G. S., Menton, R. G., 1990

机译：地塞米松剂量的疗效和药代动力学评价将降低印度恒河猴的惊厥发生率，用吡啶斯的明溴化物预处理，用索曼攻击，并用阿托品和氯化磷酸氯化物治疗

Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions

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