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Epidemiological study of soft‐tissue sarcomas in Ireland

机译:爱尔兰软组织肉瘤的流行病学研究

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摘要

Soft‐tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements. The aim of this paper is to describe the current incidence and survival of STS from 1994 to 2012 in Ireland and compare these with comparably coded international published reports. This is a retrospective, population study based on the data from the National Cancer Registry of Ireland (NCRI). Incidence and relative survival rates for STS in Ireland were generated. Incidence of STS based on gender, age and anatomical location was examined. Annual mean incidence rate (European Age Standardized) in Ireland between 1994 and 2012 was 4.48 ± 0.15 per 100,000 person‐years. The overall relative 5‐year survival rate of STS for the period 1994–2011 in Ireland was 56%, which was similar to that reported in the U.K. but lower than in most of Europe and U.S.A. Survival rate fluctuated over the period examined, declining slightly in females but showing an increase in males. STS incidence trends in Ireland were comparable to international reports. Survival trends of STS were significantly different between Ireland and other European countries, requiring further study to understand causation.
机译:软组织肉瘤(STS)占成人的1%,小儿恶性肿瘤的7%。这些罕见肿瘤的组织病理学和分类需要进一步完善。本文的目的是描述1994年至2012年爱尔兰STS的当前发生率和生存率,并将其与相应编码的国际公开报告进行比较。这是一项回顾性人群研究,基于爱尔兰国家癌症登记局(NCRI)的数据。产生了爱尔兰STS的发病率和相对生存率。根据性别,年龄和解剖位置检查了STS的发病率。 1994年至2012年之间,爱尔兰的年平均发病率(欧洲年龄标准化)为每100,000人年4.48±0.15。 1994-2011年期间,爱尔兰STS的总体相对5年生存率为56%,与英国的报告相似,但低于欧洲和美国的大多数地区。在所考察的时期内,生存率有所波动,略有下降在女性中却显示出男性的增加。爱尔兰的STS发病率趋势与国际报告相当。 STS的生存趋势在爱尔兰和其他欧洲国家之间存在显着差异,需要进一步研究以了解因果关系。

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