Plasma calcidiol calcitriol and parathyroid hormone and risk of new onset heart failure in a population‐based cohort study

摘要

BackgroundHeart failure (HF) is a major problem in the Western world, with increasing prevalence and incidence. Because HF cannot be cured, prevention of HF is of utter importance. Calcidiol, calcitriol, and parathyroid hormone (PTH) have been identified as risk factors for cardiovascular disease. However, their association with new onset HF remains to be established. We investigated whether calcidiol, calcitriol, and PTH could be used to identify those subjects at risk for new onset HF, and if they had additive predictive value over established risk predictors like N‐terminal‐pro Brain‐type natriuretic peptide and highly sensitive Troponin‐T.