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Ovarian strumal carcinoid presenting as severe progressive constipation

机译:卵巢基质类癌表现为严重进行性便秘

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摘要

Strumal carcinoid develops in a germ cell tumor characterized by an intimate mixture of thyroid and carcinoid. Unlike other carcinoid tumors, most patients with strumal carcinoid have no symptoms of carcinoid syndrome; few are reported to cause severe constipation.We report a case of a 60-year-old female patient presenting with severe progressive constipation and painful defecation for last few years. A right ovarian tumor was discovered during clinical examination. CT scan revealed a large lobulated solid cystic right adenexal mass suggestive of monomorphic teratoma, which was successfully removed surgically. The histopathology confirmed the diagnosis of strumal carcinoid tumor. Her constipation completely disappeared post surgery. These tumors are known to produce a biologically active substance like peptide YY, which has a pharmacologic inhibitory action on intestinal motility. This was presumably the cause of the constipation in this patient rather than a mechanical effect of the tumor.
机译:星形胶质瘤在生殖细胞肿瘤中发展,其特征是甲状腺和类癌的紧密混合物。与其他类癌肿瘤不同,大多数患有基质类癌的患者没有类癌综合症的症状。据报道很少有引起严重便秘的患者。我们报告了一名近60岁的女性患者,该患者最近几年出现严重的进行性便秘和痛苦的排便。在临床检查中发现了一个右卵巢肿瘤。 CT扫描显示大叶状右实性囊性囊性肿块,提示畸形畸胎瘤,已通过手术成功切除。组织病理学证实了间质类癌的诊断。术后便秘完全消失。已知这些肿瘤产生诸如肽YY的生物活性物质,其对肠蠕动具有药理学抑制作用。据推测这是该患者便秘的原因,而不是肿瘤的机械作用。

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