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A Feline‐Specific Anti‐Nerve Growth Factor Antibody Improves Mobility in Cats with Degenerative Joint Disease–Associated Pain: A Pilot Proof of Concept Study

机译：猫特异性抗神经生长因子抗体可改善患有退行性关节疾病相关性疼痛的猫的活动能力：概念研究的初步证明

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BackgroundNeutralizing antibodies against nerve growth factor (NGF) are analgesic in rodent models, naturally occurring degenerative joint disease (DJD) pain in dogs, and chronic pain in humans.

机译：背景技术针对神经生长因子（NGF）的中和性抗体在啮齿动物模型中具有镇痛作用，在狗中自然发生退化性关节疾病（DJD）疼痛，而在人类中则是慢性疼痛。

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期刊名称 Journal of Veterinary Internal Medicine
作者
M.E. Gruen; A.E. Thomson; E.H. Griffith; H. Paradise; D.P. Gearing; B.D.X. Lascelles;
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作者单位

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年(卷),期 2016(30),4
年度 2016
页码 1138–1148
总页数 11
原文格式 PDF
正文语种
中图分类动物医学（兽医学）;
关键词
Client‐specific outcome measures Feline musculoskeletal pain index Osteoarthritis;

机译：客户特定的结局指标;猫肌肉骨骼疼痛指数;骨关节炎;

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1. A Feline‐Specific Anti‐Nerve Growth Factor Antibody Improves Mobility in Cats with Degenerative Joint Disease–Associated Pain: A Pilot Proof of Concept Study [J] . Gruen M.E., Thomson A.E., Griffith E.H., Journal of Veterinary Internal Medicine . 2016,第4期

机译：猫特异性抗神经生长因子抗体可改善变性关节疾病相关性疼痛猫的活动能力：概念研究的初步证明
2. A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain [J] . B Duncan X Lascelles, David Knazovicky, Beth Case, BMC Veterinary Research . 2015,第1期

机译：犬特异性抗神经生长因子抗体可减轻与退行性关节疾病相关性疼痛的狗的疼痛并改善其活动能力和功能
3. In Vitro and In Vivo Characterization of a Fully Felinized Therapeutic Anti‐Nerve Growth Factor Monoclonal Antibody for the Treatment of Pain in Cats [J] . Gearing D.P., Huebner M., Virtue E.R., Journal of Veterinary Internal Medicine . 2016,第4期

机译：完全猫化的治疗性抗神经生长因子单克隆抗体的体外和体内表征，用于治疗猫的疼痛
4. FELINE ANTI-NERVE GROWTH FACTOR ANTIBODY IMPROVES MOBILITY IN CATS WITH DEGENERATIVE JOINT DISEASE-ASSOCIATED PAIN [C] . Margaret Gruen, Andrea Thomson, Emily Griffith, Conference of the American^College^of^Veterinary^Internal^Medicine . 2016

机译：猫抗神经生长因子抗体改善了猫的迁移率，具有退行性关节疾病相关的疼痛
5. Qualitative and Quantitative Assessment of Pain in a Naturally-Occurring Model of Feline Chronic Pain (Degenerative Joint Disease) [D] . Gruen, Margaret Elizabeth. 2016

机译：在自然发生的猫慢性疼痛（退化性关节病）模型中对疼痛进行定性和定量评估
6. A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain [O] . B Duncan X Lascelles, David Knazovicky, Beth Case, 2015

机译：犬特异性抗神经生长因子抗体可减轻与退行性关节疾病相关性疼痛的狗的疼痛并改善其活动能力和功能
7. A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain [O] . B Duncan X Lascelles, David Knazovicky, Beth Case, 2015

机译：犬特异性抗神经生长因子抗体可减轻与退行性关节疾病相关性疼痛的狗的疼痛并改善其活动性和功能

A Feline‐Specific Anti‐Nerve Growth Factor Antibody Improves Mobility in Cats with Degenerative Joint Disease–Associated Pain: A Pilot Proof of Concept Study

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