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Results of a 10‐year survey of workload for 10 treatment vaults at a high‐throughput comprehensive cancer center

机译:在高通量综合癌症中心进行的10个治疗穹顶的工作量十年调查结果

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摘要

The workload for shielding purposes of modern linear accelerators (linacs) consists of primary and scatter radiation which depends on the dose delivered to isocenter (cGy) and leakage radiation which depends on the monitor units (MUs). In this study, we report on the workload for 10 treatment vaults in terms of dose to isocenter (cGy), monitor units delivered (MUs), number of treatment sessions (Txs), as well as, use factors (U) and modulation factors (CI) for different treatment techniques. The survey was performed for the years between 2006 and 2015 and included 16 treatment machines which represent different generations of Varian linear accelerators (6EX, 600C, 2100C, 2100EX, and TrueBeam) operating at different electron and x‐ray energies (6, 9, 12, 16 and 20 MeV electrons and, 6 and 15 MV x‐rays). An institutional review board (IRB) approval was acquired to perform this study. Data regarding patient workload, dose to isocenter, number of monitor units delivered, beam energies, gantry angles, and treatment techniques were exported from an ARIA treatment management system (Varian Medical Systems, Palo Alto, Ca.) into Excel spreadsheets and data analysis was performed in Matlab. The average (± std‐dev) number of treatment sessions, dose to isocenter, and number of monitor units delivered per week per machine in 2006 was 119 ± 39 Txs, (300 ± 116) × 102 cGys, and (78 ± 28) × 103 MUs respectively. In contrast, the workload in 2015 was 112 ± 40 Txs, (337 ± 124) × 102 cGys, and (111 ± 46) × 103 MUs. 60% of the workload (cGy) was delivered using 6 MV and 30% using 15 style="fixed-case">MV while the remaining 10% was delivered using electron beams. The modulation factors ( style="fixed-case">MU/ style="fixed-case">cGy) for style="fixed-case">IMRT and style="fixed-case">VMAT were 5.0 (± 3.4) and 4.6 (± 1.6) respectively. Use factors using 90>° gantry angle intervals were equally distributed (~0.25) but varied considerably among different treatment techniques. The workload, in terms of dose to isocenter ( style="fixed-case">cGy) and subsequently monitor units ( style="fixed-case">MUs), has been steadily increasing over the past decade. This increase can be attributed to increased use of high dose hypo‐fractionated regimens ( style="fixed-case">SBRT, style="fixed-case"> SRS) and the increase in use of style="fixed-case">IMRT and style="fixed-case">VMAT, which require higher style="fixed-case">MUs per style="fixed-case">cGy as compared to more conventional treatment (3 style="fixed-case">DCRT). Meanwhile, the patient workload in terms of treatment sessions per week remained relatively constant. The findings of this report show that variables used for shielding purposes still fall within the recommendation of NCRP Report 151.
机译:现代线性加速器(直线加速器)的屏蔽工作量包括主辐射和散射辐射,后者取决于传递到等中心点的剂量(cGy),而泄漏辐射则取决于监控器(MU)。在本研究中,我们报告了10个治疗穹顶的工作量,包括等中心线剂量(cGy),监测单位递送(MUs),治疗疗程数(Txs)以及使用因子(U)和调节因子(CI)用于不同的治疗技术。该调查是在2006年至2015年之间进行的,包括16台处理机,这些处理机代表了不同世代的Varian线性加速器(6EX,600C,2100C,2100EX和TrueBeam)在不同的电子和X射线能量下运行(6、9, 12、16和20 MeV电子,6和15 MV X射线)。已获得机构审查委员会(IRB)的批准才能进行这项研究。有关患者工作量,等中心点剂量,已交付的监护仪数量,束能量,龙门架角度和治疗技术的数据从ARIA治疗管理系统(Varian Medical Systems,Palo Alto,CA)导出到Excel电子表格中,并进行了数据分析。在Matlab中执行。 2006年,平均治疗次数(±std-dev),等距剂量和每台机器每周交付的监控单元数为119±39 Txs,(300±116)×10 2 cGys和(78±28)×10 3 MU。相比之下,2015年的工作量为112±40 Txs,(337±124)×10 2 cGys和(111±46)×10 3 MU。 60%的工作量(cGy)使用6 MV输送,30%的使用15 style =“ fixed-case”> MV 输送,而其余10%则使用电子束输送。 style =“ fixed-case”> IMRT <的调制因子( style =“ fixed-case”> MU / style =“ fixed-case”> cG y) / span>和 style =“ fixed-case”> VMAT 分别为5.0(±3.4)和4.6(±1.6)。使用90°>°龙门角度间隔的使用系数平均分布(〜0.25),但在不同的处理技术之间差异很大。根据等中心点剂量( style =“ fixed-case”> cG y)和随后的监视单位( style =“ fixed-case”> MU s)的工作量,在过去十年中一直在稳定增长。这种增加可以归因于高剂量低剂量方案( style =“ fixed-case”> SBRT , style =“ fixed-case”> SRS )的使用,以及 style =“ fixed-case”> IMRT 和 style =“ fixed-case”> VMAT 的使用量增加,这需要更高的 style =“ fixed-case”> MU与更常规的治疗方法(3 style =“ fixed-case”> DCRT )相比 s。同时,就每周治疗疗程而言,患者的工作量保持相对恒定。该报告的结果表明,用于屏蔽目的的变量仍在NCRP报告151的建议之内。

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