Effects of vildagliptin as add-on treatment in patients with type 2 diabetes mellitus: insights from long-term clinical studies in Japan

机译：维格列汀作为2型糖尿病患者附加治疗的作用：来自日本长期临床研究的见解

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摘要

BackgroundVildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is wildly used to treat type 2 diabetes mellitus (T2DM) with mono- or combination-therapy. We review two previously published open-label studies to extract insights on the long-term efficacy and safety of vildagliptin.

机译：背景维尔格列汀是一种二肽基肽酶4（DPP-4）抑制剂，广泛用于通过单一疗法或联合疗法治疗2型糖尿病（T2DM）。我们回顾了两项先前发表的开放标签研究，以提取关于维格列汀的长期疗效和安全性的见解。

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期刊名称 Journal of Diabetes and Metabolic Disorders
作者
Masato Odawara; Rieko Sagara;
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作者单位

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年(卷),期 2016(15),-1
年度 2016
页码 21
总页数 9
原文格式 PDF
正文语种
中图分类基础医学;
关键词
Combination therapy Dipeptidyl peptidase-4 inhibitor Long-term administration Oral antidiabetes drugs Vildagliptin;

机译：联合疗法;Depteptidyl peptidase-4抑制剂;长期给药;口服降糖药;维格列汀;

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专利

1. Effects of insulin changes on quality of life and glycemic control in Japanese patients with type 2 diabetes mellitus: The insulin-changing study intending to gain patients' insights into insulin treatment with patient-reported health outcomes in actual clinical treatments (INSIGHTs) study [J] . IshiiH., TerauchiY., JinnouchiH., Journal of diabetes investigation. . 2013,第6期

机译：胰岛素变化对日本2型糖尿病患者生活质量和血糖控制的影响：旨在通过实际临床治疗（INSIGHTS）研究报告患者健康状况的胰岛素变化研究旨在了解患者对胰岛素治疗的见解
2. Effects of insulin changes on quality of life and glycemic control in Japanese patients with type2 diabetes mellitus: The insulin‐changing study intending to gain patients' insights into insulin treatment with patient‐reported health outcomes in actual clinical treatments (INSIGHTs) study [J] . Hideaki Jinnouchi, Hitoshi Ishii, Masakazu Takeuchi, Journal of diabetes investigation. . 2013,第6期

机译：胰岛素变化对日本2型糖尿病患者的生活质量和血糖控制的影响：旨在使患者获得更好治疗的胰岛素变化研究在实际临床治疗（INSIGHT）研究中对胰岛素治疗及患者报告的健康结局的深入了解
3. Efficacy and Safety of Vildagliptin as an Add-on to Insulin with or without Metformin in Japanese Patients with Type 2 Diabetes Mellitus: A 12-week, Double-Blind, Randomized Study. [J] . Takahisa Hirose, Manabu Suzuki, Isao Tsumiyama Diabetes therapy . 2015,第4期

机译：威格列汀在日本2型糖尿病患者中添加或不添加二甲双胍的疗效和安全性：一项为期12周的双盲随机研究。
4. Clinical observation of traditional Chinese Baduanjin Qigong (Eight trigrams boxing) in the treatment of patients with type 2 diabetes mellitus [C] . Yunchuan Wu, Feng Hao, Han Yang, International Conference on Information Technology in Medicine and Education . 2018

机译：中国传统的Baduanjin气功（八三胎拳）治疗2型糖尿病患者的临床观察
5. Recruitment, retention and compliance in randomized, phase III clinical trials involving obese patients diagnosed with type 2 Diabetes Mellitus with respect to weight loss practicum report. [D] . Mithani, Moez S. 2012

机译：涉及诊断为2型糖尿病的肥胖患者的有关减肥实践的随机III期临床试验中的招募，保留和依从性报告。
6. Effects of insulin changes on quality of life and glycemic control in Japanese patients with type 2 diabetes mellitus: The insulin‐changing study intending to gain patients insights into insulin treatment with patient‐reported health outcomes in actual clinical treatments (INSIGHTs) study [O] . Hitoshi Ishii, Yasuo Terauchi, Hideaki Jinnouchi, 2013

机译：胰岛素变化对日本2型糖尿病患者的生活质量和血糖控制的影响：旨在通过实际临床治疗（INSIGHTs）研究中患者报告的健康结局使患者对胰岛素治疗有深刻见解的胰岛素变化研究
7. Effects of vildagliptin as add-on treatment in patients with type 2 diabetes mellitus: insights from long-term clinical studies in Japan [O] . 2016

机译：维格列汀作为2型糖尿病患者附加治疗的作用：来自日本长期临床研究的见解

Effects of vildagliptin as add-on treatment in patients with type 2 diabetes mellitus: insights from long-term clinical studies in Japan

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