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Predicting Bleeding Events in Anticoagulated Patients With Atrial Fibrillation: A Comparison Between the HAS‐BLED and GARFIELD‐AF Bleeding Scores

机译:预测抗凝性房颤患者的出血事件:HAS-BLED和GARFIELD-AF出血评分之间的比较

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摘要

BackgroundPatients with atrial fibrillation (AF) treated with oral anticoagulants may be exposed to an increased risk of bleeding events. The HAS‐BLED (Hypertension, Abnormal renal and liver function, Stroke, Bleeding, Labile INRs, Elderly, Drugs or alcohol) score is a simple, well‐established, clinical bleeding‐risk prediction score. Recently, a new algorithm‐based score was proposed, the GARFIELD‐AF (Global Anticoagulant in the Field–AF) bleeding score. We compared HAS‐BLED and GARFIELD‐AF scores in predicting adjudicated bleeding events in a clinical trial cohort of patients with AF taking anticoagulants, in the first external comparative validation of both scores.
机译:背景经口服抗凝剂治疗的房颤患者可能会增加出血事件的风险。 HAS-BLED(高血压,肾和肝功能异常,中风,出血,不稳定的INR,老年人,药物或酒精)评分是一项简单的,公认的临床出血风险预测评分。最近,提出了一种基于算法的新评分,即GARFIELD-AF(全球抗凝药在现场–AF)出血评分。我们在首次外部比较验证中,比较了HAS-BLED和GARFIELD-AF评分在预测接受抗凝治疗的AF患者的临床试验队列中的判定性出血事件中的价值。

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