Feasibility of intraoperative detection of sentinel lymph nodes with 89-zirconium-labelled nanocolloidal albumin PET-CT and a handheld high-energy gamma probe

摘要

BackgroundPET/CT lymphoscintigraphy using ⁸⁹Zr-nanocolloidal albumin has the potential to improve the preoperative identification of sentinel lymph nodes (SLNs), especially if located in the near proximity of the primary tumour. This study aims to demonstrate the feasibility of PET/CT lymphoscintigraphy followed by intraoperative detection of ⁸⁹Zr-nanocolloidal albumin containing SLNs with the use of a handheld high-energy gamma probe.