OPTICAL-IMAGING PROBE FOR DETECTING SENTINEL LYMPH NODES WHICH CONTAINS A COMPOSITE OF POLY-GAMMA-GLUTAMIC ACID AND AN OPTICAL-IMAGING DIE

摘要

The present invention relates to an optical-imaging probe for detecting sentinel lymph nodes which contains a composite of poly-gamma-glutamic acid and an optical-imaging die, and more specifically relates to an optical-imaging probe for detecting sentinel lymph nodes which contains a composite of poly-gamma-glutamic acid and an optical fluorescent die that remains for a relatively long time in sentinel lymph nodes and undergoes little migration to other lymph nodes when injected subcutaneously into a living body. The present invention involves the use of poly-gamma-glutamic acid and a fluorescent dye that is stable in living bodies without the use of any existing radiopharmaceutical, and thus allows precise real-time detection of the position of sentinel lymph nodes without any risk of contamination by radioactivity.