HIV-1 Drug Resistance and Third-Line Therapy Outcomes in Patients Failing Second-Line Therapy in Zimbabwe

机译：津巴布韦二线治疗失败的患者的HIV-1耐药性和三线治疗结果

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摘要

ObjectivesTo analyze the patterns and risk factors of HIV drug resistance mutations among patients failing second-line treatment and to describe early treatment responses to recommended third-line antiretroviral therapy (ART) in a national referral HIV clinic in Zimbabwe.

机译：目的分析在二线治疗失败的患者中HIV耐药性突变的模式和危险因素，并描述津巴布韦全国转诊HIV诊所对推荐的三线抗逆转录病毒疗法（ART）的早期治疗反应。

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期刊名称 Open Forum Infectious Diseases
作者
Cleophas Chimbetete; David Katzenstein; Tinei Shamu; Adrian Spoerri; Janne Estill; Matthias Egger; Olivia Keiser;
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作者单位

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年(卷),期 2018(5),2
年度 2018
页码 ofy005
总页数 8
原文格式 PDF
正文语种
中图分类病毒传染病;
关键词
HIV-1 drug resistance second-line therapy third-line ART outcomes Zimbabwe;

机译：HIV-1耐药性;二线治疗;三线ART结局;津巴布韦;

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专利

1. HIV-1 Drug Resistance and Third-Line Therapy Outcomes in Patients Failing Second-Line Therapy in Zimbabwe [J] . Cleophas Chimbetete, Janne Estill, Matthias Egger, Open Forum Infectious Diseases . 2018,第2期

机译：津巴布韦二线治疗失败的患者的HIV-1耐药性和第三线治疗结果
2. Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa [J] . Adetayo Emmanuel Obasa, Anoop T. Ambikan, Soham Gupta, BMC Infectious Diseases . 2021,第1期

机译：来自南非国家二线治疗失败的受感染患者的次要HIV-1 Quasispecies中获得的蛋白酶抑制剂抗药性突变增加
3. Predicting the Need for Third-Line Antiretroviral Therapy by Identifying Patients at High Risk for Failing Second-Line Antiretroviral Therapy in South Africa [J] . Onoya Dorina, Nattey Cornelius, Budgell Eric, AIDS patient care and STDs . 2017,第5期

机译：通过鉴定南非第二线抗逆转录病毒治疗的高风险鉴定患者需要鉴定第三线抗逆转录病毒治疗的需要
4. Association of Multi-Drug Resistance-1 (MDR1) Gene Polymorphism with Leukocytopenia in Breast Cancer Patients treated with Chemotherapy [C] . Siti Syarifah, Tri Widyawati, Kamal B. Siregar, Public Health International Conference . 2017

机译：化疗治疗乳腺癌患者白细胞凋亡的多药抗性-1（MDR1）基因多态性的关联
5. Phenotypic analysis of HIV-1 drug resistance during highly active antiretroviral therapy (HAART). [D] . Zhang, Haili. 2005

机译：高效抗逆转录病毒疗法（HAART）期间HIV-1耐药性的表型分析。
6. Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa [O] . Adetayo Emmanuel Obasa, Anoop T. Ambikan, Soham Gupta, 2021

机译：增加了受感染患者在南非国家二线治疗失败的感染患者中患有次要HIV-1 Quaspecies中的蛋白酶抑制剂抗药性突变
7. HIV-1 Drug Resistance and Third-Line Therapy Outcomes in Patients Failing Second-Line Therapy in Zimbabwe [O] . Cleophas Chimbetete, David Katzenstein, Tinei Shamu, 2018

机译：津巴布韦二线治疗失败的患者的HIV-1耐药性和第三线治疗结果

HIV-1 Drug Resistance and Third-Line Therapy Outcomes in Patients Failing Second-Line Therapy in Zimbabwe

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