Value of cytokeratin-19 Hector Battifora mesothelial-1 and galectin-3 immunostaining in the diagnosis of thyroid neoplasms

摘要

BACKGROUND:Diagnosis of types and aggressiveness of thyroid cancers is difficult. The “gold standard” in diagnosis is using routine hematoxylin and eosin staining. Several markers have been investigated for differentiating them among which cytokeratin-19 (CK-19), Hector Battifora mesothelial cell (HBME-1), and galectin-3 are found to be most commonly used. Most studies have evaluated the single expression of markers in various thyroid lesions.