IntroductionA 52-year-old man presented with extensive bilateral inflammatory myositis of the quadriceps on a background of pyrexia of unknown origin (PUO). He had markedly elevated acute phase reactants but had a normal CK and did not develop muscle weakness. This was a transient phenomenon which resolved spontaneously over 10 weeks. There was not an infective process identified and he was not treated with glucocorticoids or other immunosuppressants. This case highlights the importance of careful consideration of steroid treatment in atypical presentations without a clear diagnosis and the value of multidisciplinary involvement in patient care.
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