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Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway

机译：β2肾上腺素能受体和生长抑素受体5的异源二聚化：对信号传导途径的调节作用

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摘要

BackgroundIn the present study, we describe heterodimerization between human-Somatostatin Receptor 5 (hSSTR5) and β2-Adrenergic Receptor (β2AR) and its impact on the receptor trafficking, coupling to adenylyl cyclase and signaling including mitogen activated protein kinases and calcineurin-NFAT pathways.

机译：背景技术在本研究中，我们描述了人生长抑素受体5（hSSTR5）和β2-肾上腺素能受体（β2AR）之间的异源二聚化及其对受体运输的影响，与腺苷酸环化酶的耦合以及包括促分裂原活化蛋白激酶和钙调神经磷酸酶-NFAT信号通路的信号传导。

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期刊名称 Journal of Molecular Signaling
作者
Rishi K Somvanshi; Nicole Chaudhari; Xiaofan Qiu; Ujendra Kumar;
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作者单位

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年(卷),期 2011(6),-1
年度 2011
页码 9
总页数 17
原文格式 PDF
正文语种
中图分类分子生物学 ;
关键词
G-protein-coupled receptor Human somatostatin receptor-5; β2 adrenergic receptors; Heterodimerization; Photobleaching-fluorescence resonance energy transfer and Somatostatin;

机译：G蛋白偶联受体;人类生长抑素受体5;β2肾上腺素受体;异二聚化;光漂白-荧光共振能量转移和生长抑素;

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专利

1. Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway [J] . Rishi K Somvanshi, Nicole Chaudhari, Xiaofan Qiu, Journal of molecular signaling . 2011 ,第1期

机译：β2肾上腺素能受体和生长抑素受体5的异源二聚化：对信号传导途径的调节作用
2. Receptor specific crosstalk and modulation of signaling upon heterodimerization between β_1-adrenergic receptor and somatostatin receptor-5 [J] . Somvanshi R.K., War S.A., Chaudhari N., Cellular Signalling . 2011 ,第5期

机译：β_1-肾上腺素能受体与生长抑素受体-5之间异源二聚体的受体特异性串扰和信号传导的调节
3. Somatostatin receptors 1 and 5 heterodimerize with epidermal growth factor receptor: Agonist-dependent modulation of the downstream MAPK signalling pathway in breast cancer cells [J] . Watt HL, Kharmate GD, Kumar U Cellular Signalling . 2009 ,第3期

机译：生长抑素受体1和5与表皮生长因子受体异源二聚体：乳腺癌细胞下游MAPK信号通路的激动剂依赖性调节
4. Monitoring receptor heterodimerization along intracellular trafficking pathways using anti-HER2 therapeutic antibodies [C] . Alena Rudkouskaya, Jason Smith, Xavier Intes, Conference on Visualizing and Quantifying Drug Distribution in Tissue . 2021

机译：使用抗HER2治疗性抗体监测沿细胞内运输途径的受体异二聚体
5. Interactions between the cannabinoid and the beta-adrenergic systems: Receptor heterodimerization, signalling interactions and the regulation of intraocular pressure. [D] . Hudson, Brian David. 2010

机译：大麻素与β-肾上腺素系统之间的相互作用：受体异源二聚化，信号相互作用和眼压调节。
6. δ-Opioid Receptor and Somatostatin Receptor-4 Heterodimerization: Possible Implications in Modulation of Pain Associated Signaling [O] . Rishi K. Somvanshi, Ujendra Kumar -1

机译：δ阿片受体和生长抑素受体4异二聚化：疼痛相关信号的调制中的可能含义。
7. Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway [O] . Somvanshi, Rishi K, Chaudhari, Nicole, Qiu, Xiaofan, 2011

机译：β2肾上腺素能受体和生长抑素受体5的异源二聚化：对信号传导途径的调节作用
8. Controlling Homo- & Heterodimerization of ErbB Receptors Using Synthetic Ligands and Understanding the RTK Heterodimer Signaling Specificity in Breast Cancer [R] . Muthuswamy, S. 1999

机译：使用合成配体控制ErbB受体的同源和异二聚化并了解乳腺癌中的RTK异二聚体信号特异性

Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway

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