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Microparticles controllable accumulation arrangement and spatial shaping performed by tapered-fiber-based laser-induced convection flow

机译:通过基于锥形纤维的激光诱导对流进行的微粒可控累积排列和空间整形

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摘要

The ability to arrange cells and/or microparticles into the desired pattern is critical in biological, chemical, and metamaterial studies and other applications. Researchers have developed a variety of patterning techniques, which either have a limited capacity to simultaneously trap massive particles or lack the spatial resolution necessary to manipulate individual particle. Several approaches have been proposed that combine both high spatial selectivity and high throughput simultaneously. However, those methods are complex and difficult to fabricate. In this article, we propose and demonstrate a simple method that combines the laser-induced convection flow and fiber-based optical trapping methods to perform both regular and special spatial shaping arrangement. Essentially, we combine a light field with a large optical intensity gradient distribution and a thermal field with a large temperature gradient distribution to perform the microparticles shaping arrangement. The tapered-fiber-based laser-induced convection flow provides not only the batch manipulation of massive particles, but also the finer manipulation of special one or several particles, which break out the limit of single-fiber-based massive/individual particles photothermal manipulation. The combination technique allows for microparticles quick accumulation, single-layer and multilayer arrangement; special spatial shaping arrangement/adjustment, and microparticles sorting.
机译:将细胞和/或微粒排列成所需模式的能力在生物学,化学和超材料研究以及其他应用中至关重要。研究人员已经开发出各种构图技术,这些技术要么具有有限的能力来同时捕获大颗粒,要么缺乏操纵单个颗粒所需的空间分辨率。已经提出了将高空间选择性和高通量同时结合的几种方法。但是,这些方法很复杂并且难以制造。在本文中,我们提出并演示了一种简单的方法,该方法结合了激光诱导的对流流动和基于光纤的光学陷波方法,以执行规则的和特殊的空间整形布置。本质上,我们将光强度梯度分布较大的光场和温度梯度分布较大的热场组合在一起,以进行微粒成形。基于锥形纤维的激光诱导对流不仅提供对大颗粒的分批处理,而且还提供了对一个或多个特殊颗粒的精细处理,从而突破了基于单纤维的大/单个颗粒光热处理的局限性。结合技术可实现微粒的快速堆积,单层和多层排列;特殊的空间整形布置/调整以及微粒分类。

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