Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E

摘要

BackgroundThe present study takes advantage of the beneficial effects of resveratrol as a neuroprotective compound. Resveratrol-loaded solid lipid nanoparticles were functionalized with apolipoprotein E which can be recognized by the LDL receptors overexpressed on the blood–brain barrier.