In Vitro Study of Antiadipogenic Profile of Latanoprost Travoprost Bimatoprost and Tafluprost in Human Orbital Preadiopocytes

摘要

PurposeTo investigate the effect of prostaglandin F2α (PGF2α), latanoprost, travoprost, bimatoprost, and tafluprost on human orbital preadipocyte differentiation and intracellular lipid storage, and to reveal the potential mechanisms by which topical prostaglandin analogs induce orbital fat volume reduction and cause deep superior sulcus syndrome.