p16/Ki-67 Dual Stain Cytology for Detection of Cervical Precancer in HPV-Positive Women

摘要

Background:Human papillomavirus (HPV)–based cervical cancer screening requires triage markers to decide who should be referred to colposcopy. p16/Ki-67 dual stain cytology has been proposed as a biomarker for cervical precancers. We evaluated the dual stain in a large population of HPV-positive women.