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Advanced Stage Increased Lactate Dehydrogenase and Primary Site but Not Adolescent Age (≥ 15 Years) Are Associated With an Increased Risk of Treatment Failure in Children and Adolescents With Mature B-Cell Non-Hodgkins Lymphoma: Results of the FAB LMB 96 Study

机译：晚期乳酸脱氢酶增加和原发部位增加但未达到青少年年龄（≥15岁）会增加患有成熟B细胞非霍奇金淋巴瘤的儿童和青少年治疗失败的风险增加：FAB LMB的结果96研究

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PurposeAdolescents (age 15 to 21 years) compared with younger children with mature B-cell non-Hodgkin's lymphoma (NHL) have been historically considered to have an inferior prognosis. We therefore analyzed the impact of age and other diagnostic factors on the risk of treatment failure in children and adolescents treated on the French-American-British Mature B-Cell Lymphoma 96 (FAB LMB 96) trial.

机译：目的从历史上看，青少年（年龄在15至21岁之间）与年龄较轻的成熟B细胞非霍奇金淋巴瘤（NHL）儿童相比，预后较差。因此，我们在法美英英成熟B细胞淋巴瘤96（FAB LMB 96）试验中分析了年龄和其他诊断因素对儿童和青少年治疗失败风险的影响。

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期刊名称 Journal of Clinical Oncology
作者
Mitchell S. Cairo; Richard Sposto; Mary Gerrard; Anne Auperin; Stanton C. Goldman; Lauren Harrison; Ross Pinkerton; Martine Raphael; Keith McCarthy; Sherrie L. Perkins; Catherine Patte;
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作者单位

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年(卷),期 -1(30),4
年度 -1
页码 387–393
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
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1. Advanced stage, increased lactate dehydrogenase, and primary site, but not adolescent age ( ≥15 years), are associated with an increased risk of treatment failure in children and adolescents with mature B-cell non-Hodgkin's lymphoma: Results of the FAB LMB 96 study [J] . CairoM.S., SpostoR., GerrardM., Journal of Clinical Oncology . 2012,第4期

机译：晚期，乳酸脱氢酶增加和原发部位增加，但未达到青少年年龄（≥15岁），则伴有成熟B细胞非霍奇金淋巴瘤的儿童和青少年的治疗失败风险增加：FAB LMB的结果96研究
2. Overall survival of children and adolescents with mature B cell non‐Hodgkin lymphoma who had refractory or relapsed disease during or after treatment with FAB FAB / LMB LMB 96: A report from the FAB FAB / LMB LMB 96 study group [J] . Cairo Mitchell, Auperin Anne, Perkins Sherrie L., British Journal of Haematology . 2018,第6期

机译：儿童和青少年的整体生存与成熟的B细胞非霍奇金淋巴瘤在用Fab Fab / LMB 96治疗期间或后患有难治性或复发的疾病：来自Fab Fab / LMB LMB 96研究组的报告
3. Specific cytogenetic abnormalities are associated with a significantly inferior outcome in children and adolescents with mature B-cell non-Hodgkin's lymphoma: results of the FAB|[sol]|LMB 96 international study [J] . H A Poirel, M S Cairo, N A Heerema, Leukemia . 2009,第2期

机译：特异性细胞遗传学异常与患有成熟B细胞非霍奇金淋巴瘤的儿童和青少年的显着劣等的结果相关：工厂的结果| [SOL] | LMB 96国际研究
4. Screening for Developmental Delay in At-Risk Children: Ages and Stages. Questionnaire in an Adolescent Primary Care Clinic [D] . Zelinger, Jordan. 2014

机译：筛查有风险的儿童的发育迟缓：年龄和阶段。青春期初级保健诊所问卷
5. Overall survival of children and adolescents with mature B cell non-Hodgkin lymphoma who had refractory or relapsed disease during or after treatment with FAB/LMB 96: A report from the FAB/LMB 96 study group [O] . Mitchell Cairo, Anne Auperin, Sherrie L. Perkins, -1

机译：FAB / LMB 96治疗期间或之后患有难治性或复发性疾病的成熟B细胞非霍奇金淋巴瘤儿童和青少年的总体生存期：FAB / LMB 96研究组的报告
6. Advanced stage, increased lactate dehydrogenase, and primary site, but not adolescent age ( ≥15 years), are associated with an increased risk of treatment failure in children and adolescents with mature B-cell non-Hodgkin\u27s lymphoma: results of the FAB [O] . Cairo, Mitchell S., Sposto, Richard, Gerrard, Mary, 2012

机译：晚期，乳酸脱氢酶增加和原发部位增加，但未达到青少年年龄（≥15岁），与患有成熟B细胞非霍奇金淋巴瘤的儿童和青少年的治疗失败风险增加相关：FAB结果

Advanced Stage Increased Lactate Dehydrogenase and Primary Site but Not Adolescent Age (≥ 15 Years) Are Associated With an Increased Risk of Treatment Failure in Children and Adolescents With Mature B-Cell Non-Hodgkins Lymphoma: Results of the FAB LMB 96 Study

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