Differences in Human Meibum Lipid Composition with Meibomian Gland Dysfunction Using NMR and Principal Component Analysis

摘要

Purpose.Nuclear magnetic resonance (NMR) spectroscopy has been used to quantify lipid wax, cholesterol ester terpenoid and glyceride composition, saturation, oxidation, and CH2 and CH3 moiety distribution. This tool was used to measure changes in human meibum composition with meibomian gland dysfunction (MGD).