Therapeutic Effects of PPARα Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration

机译：PPARα激动剂对新生血管性年龄相关性黄斑变性模型中眼新血管形成的治疗作用

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PurposeThis study was designed to evaluate effects of fenofibric acid (Feno-FA), a peroxisome proliferator–activated receptor-alpha (PPARα) agonist, on ocular neovascularization (NV) in models recapitulating neovascular age-related macular degeneration (AMD), and to explore whether the effects are PPARα dependent.

机译：目的本研究旨在评估过氧化物酶体增殖物激活受体-α（PPARα）激动剂非诺贝特酸（Feno-FA）对概括新生血管性年龄相关性黄斑变性（AMD）的模型中眼新血管形成（NV）的影响，以及探索这些作用是否与PPARα有关。

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期刊名称 Investigative Ophthalmology Visual Science
作者
Fangfang Qiu; Greg Matlock; Qian Chen; Kelu Zhou; Yanhong Du; Xiang Wang; Jian-Xing Ma;
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作者单位

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年(卷),期 -1(58),12
年度 -1
页码 5065–5075
总页数 11
原文格式 PDF
正文语种
中图分类眼科学;
关键词
age-related macular degeneration PPARα fenofibrate inflammation retina neovascularization;

机译：与年龄有关的黄斑变性;PPARα;非诺贝特;炎症;视网膜;新血管形成;

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专利

1. Therapeutic Effects of PPAR?± Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration [J] . Fangfang Qiu, Greg Matlock, Qian Chen, Investigative ophthalmology & visual science . 2017,第12期

机译：PPARα±激动剂对新生血管性年龄相关性黄斑变性模型中眼新血管形成的治疗作用
2. Therapeutic Effects of PPAR alpha Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration [J] . Qiu Fangfang, Matlock Greg, Chen Qian, Investigative ophthalmology & visual science . 2017,第12期

机译：PPARα激动剂对综合新生血管年龄相关性黄斑变性的模型眼血管形成的治疗效果
3. Therapeutic Effects of PPAR alpha Agonist on Experimental Neovascular Age-Related Macular Degeneration [J] . Qiu Fangfang, Matlock H. Greg, Chen Qian, Investigative ophthalmology & visual science . 2017,第8期

机译：PPARα激动剂对实验新生血管年龄相关性黄斑变性的治疗效果
4. Assessment of Choroidal Neovascular Membranes Secondary to Age-Related Macular Degeneration Using Feature Selection [C] . E. Brankin, P.J. McCullagh, W.P. Patton European Conference of the International Federation for Medical and Biological Engineering . 2013

机译：用特征选择评估二次与年龄相关黄斑变性的脉络膜新生血管膜
5. A model for choroidal neovascularization (CNV) and gene therapy for age-related macular degeneration (AMD). [D] . Wang, Fei. 2001

机译：脉络膜新生血管（CNV）和年龄相关性黄斑变性（AMD）基因治疗的模型。
6. Cytokine and Chemokine Profile Changes in Patients with Neovascular Age-Related Macular Degeneration After Intravitreal Ranibizumab Injection for Choroidal Neovascularization [O] . Tingting Sun, Qingquan Wei, Peng Gao, 2021

机译：细胞因子和趋化因子概况术治术后术治疗脉络膜新生血管术后新生血管年龄相关性黄斑变性的患者
7. Therapeutic Effects of PPARα Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration [O] . Fangfang Qiu, Greg Matlock, Qian Chen, 2017

机译：PPARα激动剂对综合血管时代相关黄斑变性模型眼血管形成的疗效

Therapeutic Effects of PPARα Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration

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