miR-200a Prevents Renal Fibrogenesis Through Repression of TGF-β2 Expression

摘要

OBJECTIVEProgressive fibrosis in the diabetic kidney is driven and sustained by a diverse range of profibrotic factors. This study examines the critical role of microRNAs (miRNAs) in the regulation of the key fibrotic mediators, TGF-β1 and TGF-β2.