Dynamics of bone turnover markers in patients with heart failure and following haemodynamic improvement through ventricular assist device implantation

摘要

AimsAbnormal bone metabolism and progressive demineralization have been described in patients with heart failure (HF). We hypothesized that mechanical unloading through implantation of a ventricular assist device (VAD) with subsequent haemodynamic improvement would correct abnormal bone metabolism in patients with advanced HF.