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Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer

机译:皮质类固醇激素可缓解晚期妇科和胃肠道恶性肠梗阻

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摘要

BackgroundThis is an update of the review published in Issue 3, 1999. Gastrointestinal and ovarian cancers are common cancers. The incidence of associated malignant bowel obstruction in patients with advanced cancers of these types is not known, and the best management of these patients is controversial. Inappropriate management may result in uncontrolled (faeculant) vomiting, pain and distress. Management of the symptoms can include palliative surgery, nasogastric tube suction together with intravenous fluids, or pharmacological means, such as corticosteroids. There is uncertainty regarding both the efficacy and possible harmful effects of corticosteroids, and also the most effective type, dose/dosing regime, route and period of administration.
机译:背景信息这是对1999年第3期发表的综述的更新。胃肠道和卵巢癌是常见的癌症。这些类型的晚期癌症患者中相关的恶性肠梗阻的发生率尚不清楚,这些患者的最佳治疗尚存争议。处理不当可能会导致无法控制的(剧烈的)呕吐,疼痛和痛苦。症状的处理可以包括姑息手术,鼻胃管抽吸以及静脉输液或药理手段,例如皮质类固醇。关于皮质类固醇的功效和可能的有害作用,以及最有效的类型,剂量/给药方式,给药途径和时间,尚不确定。

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