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A randomized phase III study comparing pegylated liposomal doxorubicin with capecitabine as first-line chemotherapy in elderly patients with metastatic breast cancer: results of the OMEGA study of the Dutch Breast Cancer Research Group BOOG

机译：一项比较老年患者转移性乳腺癌的聚乙二醇化脂质体阿霉素与卡培他滨作为一线化疗的III期随机研究：荷兰乳腺癌研究小组BOOG的OMEGA研究结果

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BackgroundProspective data on chemotherapy for elderly patients with metastatic breast cancer (MBC) remain scarce. We compared the efficacy and safety of first-line chemotherapy with pegylated liposomal doxorubicin (PLD) versus capecitabine in MBC patients aged ≥65 years in a multicentre, phase III trial.

机译：背景老年转移性乳腺癌（MBC）患者化疗的前瞻性数据仍然很少。在一项多中心III期试验中，我们比较了聚乙二醇脂质体阿霉素（PLD）与卡培他滨一线化疗对≥65岁的MBC患者的疗效和安全性。

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期刊名称 Annals of Oncology
作者
C. H. Smorenburg; S. M. de Groot; A. E. van Leeuwen-Stok; M. E. Hamaker; A. N. Wymenga; H. de Graaf; F. E. de Jongh; J. J. Braun; M. Los; E. Maartense; H. van Tinteren; J. W. R. Nortier; C. Seynaeve;
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年(卷),期 -1(25),3
年度 -1
页码 599–605
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
metastatic breast cancer capecitabine pegylated liposomal doxorubicin phase III elderly geriatric;

机译：转移性乳腺癌;卡培他滨;聚乙二醇脂质体阿霉素;III期;老年;老年;

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1. 来自一项艾日布林联合吉西他滨对比紫杉醇联合吉西他滨作为HER2阴性转移性乳腺癌的一线化疗的II期、多中心、随机试验的包含神经病变相关量表的生活质量结果:韩国癌症研究组试验(KCSG BR13-11) [J] . Ji-Yeon Kim, Young-Hyuck Im, Tae-Yong Kim, 癌症（英文版） . 2019,第008期
2. A randomized phase III study comparing pegylated liposomal doxorubicin with capecitabine as first-line chemotherapy in elderly patients with metastatic breast cancer: Results of the OMEGA study of the Dutch Breast Cancer Research Group BOOG [J] . SmorenburgC.H., DeGrootS.M., VanLeeuwen-StokA.E., Annals of oncology: official journal of the European Society for Medical Oncology . 2014,第3期

机译：一项III期随机研究比较了聚乙二醇脂质体阿霉素和卡培他滨作为老年转移性乳腺癌患者的一线化疗：荷兰乳腺癌研究小组BOOG的OMEGA研究结果
3. A randomized phase III study evaluating pegylated liposomal doxorubicin versus capecitabine as first-line therapy for metastatic breast cancer: results of the PELICAN study [J] . Harbeck Nadia, Saupe Steffen, Jaeger Elke, Breast cancer research and treatment. . 2017,第1期

机译：评估聚乙二醇化脂质体DOXORUBICIN与Capecitabine作为转移性乳腺癌的一线治疗的随机阶段III研究：鹈鹕研究的结果
4. Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: results of a Dutch Community Setting Trial for the Clinical Trial Gro [J] . Bontenbal M, Creemers GJ, Braun HJ, Journal of Clinical Oncology . 2005,第28期

机译：II至III期研究比较阿霉素和多西紫杉醇与氟尿嘧啶，阿霉素和环磷酰胺作为转移性乳腺癌患者的一线化疗：荷兰社区临床试验设置的结果Gro
5. Correlations between depressive symptoms and quality of life in metastatic breast cancer patients during chemotherapy [C] . Dragomir B.I., Campean A. European Association of Psychosomatic Medicine., Annual Meeting. . 2014

机译：化疗期间转移性乳腺癌患者抑郁症状与生活质量的相关性
6. Investigating age varying effect of access to cancer care on immediate choice of chemotherapy among elderly women with metastatic breast cancer. [D] . Wan, Shaowei. 2010

机译：调查在转移性乳腺癌的老年妇女中，癌症治疗对立即选择化疗的年龄差异影响。
7. A randomized phase III study evaluating pegylated liposomal doxorubicin versus capecitabine as first-line therapy for metastatic breast cancer: results of the PELICAN study [O] . Nadia Harbeck, Steffen Saupe, Elke Jäger, -1

机译：评价聚乙二醇化脂质体阿霉素和卡培他滨作为转移性乳腺癌的一线治疗的随机III期研究：PELICAN研究的结果
8. A randomized phase III study comparing pegylated liposomal doxorubicin with capecitabine as first-line chemotherapy in elderly patients with metastatic breast cancer: results of the OMEGA study of the Dutch Breast Cancer Research Group BOOG [O] . C.H. Smorenburg, S.M. de Groot, A.E. van Leeuwen-Stok, 2014

机译：随机期III研究将Pegymated脂质体Doxorubicin与Capecitabine作为老年转移性乳腺癌患者的一线化疗进行比较：荷兰乳腺癌研究组Boog的Omega研究结果

A randomized phase III study comparing pegylated liposomal doxorubicin with capecitabine as first-line chemotherapy in elderly patients with metastatic breast cancer: results of the OMEGA study of the Dutch Breast Cancer Research Group BOOG

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