Ethyl 6-methyl-4-2-(4455-tetra­methyl-132-dioxaborolan-2-yl)thio­phen-3-yl-2-thioxo-1234-tetra­hydro­pyrimidine-5-carboxyl­ate

摘要

A new Biginelli compound, C18H25BN2O4S2, containing a boronate ester group was synthesized from a lithium bromide-catalysed reaction. The compound crystallizes with two independent mol­ecules in the asymmetric unit that differ mainly in the conformation of the ester functionality. The crystal structure is stabilized by inter­molecular N—H⋯O and N—H⋯S hydrogen bonds involving the 3,4-dihydro­pyrimidine-2(1H)-thione NH groups as donors and the carbonyl O and thio­phene S atoms as acceptors.