THE RISK OF COBALAMIN DEFICIENCY SYMPTOMS RELATED TO LONG-TERM METFORMIN USE IN T2DM PATIENTS

摘要

BackgroundMetformin is the first-line oral antidiabetic agent used in the treatment of diabetes mellitus. One of the adverse reactions of the long term use of metformin is cobalamin malabsorption. Clinical and laboratory findings are important in the diagnosis of cobalamin deficiency.