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Alternanthera mosaic potexvirus: Several Features Properties and Application

机译:Alternanthera马赛克potexvirus:若干功能特性和应用

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摘要

Alternanthera mosaic virus (AltMV) is a typical member of the Potexvirus genus in its morphology and genome structure; still it exhibits a number of unique features. They allow this virus to be considered a promising object for biotechnology. Virions and virus-like particles (VLPs) of AltMV are stable in a wide range of conditions, including sera of laboratory animals. AltMV VLPs can assemble at various pH and ionic strengths. Furthermore, AltMV virions and VLPs demonstrate high immunogenicity, enhancing the immune response to the target antigen thus offering the possibility of being used as potential adjuvants. Recently, for the first time for plant viruses, we showed the structural difference between morphologically similar viral and virus-like particles on AltMV virions and VLPs. In this review, we discuss the features of AltMV virions, AltMV VLP assembly, and their structure and properties, as well as the characteristics of AltMV isolates, host plants, infection symptoms, AltMV isolation and purification, genome structure, viral proteins, and AltMV-based vectors.
机译:轮虫花叶病毒(AltMV)在形态和基因组结构上是痘病毒属的典型成员。它仍然具有许多独特的功能。他们使这种病毒被认为是生物技术的有希望的对象。 AltMV的病毒颗粒和病毒样颗粒(VLP)在广泛的条件下(包括实验室动物的血清)均稳定。 AltMV VLP可以在各种pH和离子强度下组装。此外,AltMV病毒体和VLP表现出高免疫原性,增强了对靶抗原的免疫反应,因此提供了用作潜在佐剂的可能性。最近,对于植物病毒,我们首次展示了AltMV病毒体和VLP上形态相似的病毒颗粒和病毒样颗粒之间的结构差异。在这篇综述中,我们讨论了AltMV病毒体的特征,AltMV VLP装配及其结构和性质,以及AltMV分离株,宿主植物,感染症状,AltMV分离和纯化,基因组结构,病毒蛋白和AltMV的特征。基于向量。

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