Detection of HIV-1 and Human Proteins in Urinary Extracellular Vesicles from HIV+ Patients

摘要

Background Extracellular vesicles (EVs) are membrane bound, secreted by cells, and detected in bodily fluids, including urine, and contain proteins, RNA, and DNA. Our goal was to identify HIV and human proteins (HPs) in urinary EVs from HIV+ patients and compare them to HIV− samples.