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Informed consent by children and participation in an influenza vaccine trial.

机译:儿童知情同意并参加流感疫苗试验。

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摘要

Two hundred thirteen school children, ages six to nine, were presented the opportunity to participate in an experimental trial of swine influenza vaccine. In non-directive question and answer sessions, all groups of children except one composed only of six year olds elicited all relevant information on the details of the trial and the associated risks and benefits. Forty-six per cent of the subjects declined to participate. Letters requiring informed consent of the parents were sent to the homes of the others. Almost 15 per cent of these parents agreed to their children's participation. In this setting, children initiate their own visits to the school nurse practitioner. A significant association was found between volunteering for the study and higher use of services (but not for medical reasons). Younger children and boys, regardless of their patterns of use, were less inclined to volunteer for the experiment.
机译:213名6至9岁的学童有机会参加猪流感疫苗的实验性试验。在非指示性问答环节中,除仅由六岁儿童组成的一组儿童以外,所有其他儿童组均获得了有关试验细节以及相关风险和收益的所有相关信息。 46%的受试者拒绝参加。需要父母知情同意的信件被发送到了其他人的家中。这些父母中几乎有15%同意孩子的参与。在这种情况下,孩子们可以自己开始拜访学校的护士。发现自愿参加研究与更高程度使用服务之间存在显着关联(但并非出于医疗原因)。年龄较小的男孩和儿童,无论使用方式如何,都不太愿意自愿参加实验。

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