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The accurate surgical margin before surgery for malignant musculoskeletal tumors: a retrospective study

机译:恶性肌肉骨骼肿瘤手术前准确的手术切缘:一项回顾性研究

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摘要

There is no accurate volume measurement method for evaluating the response to chemotherapy in malignant musculoskelal tumors, and there is no specific preoperative evaluation method to evaluate surgical margins. Twenty-five cases of malignant musculoskeletal tumors treated from Mar 2012 to Mar 2014 were analyzed. Through the use of a connective slice-scan and augmented virtual reality technique, accurate measurement of the tumor volume and determination of surgical margins according to the standard proposed by Kawaguchi were easily reached. Specimens were sent for a pathological examination to determine the tumor type. The preoperative surgical margin was compared with the postoperative surgical margin. Curative resection or wide resection facilitated by the preoperative imaging data occurred in 92% of patients; only one case resulted in intralesional resection for malignant tumor progression, and one case resulted in marginal resection for femoral nerve invasion. There was no significant difference between the predicted margin before the operation and final margin after the operation (P>0.05). Our results demonstrate that application of continuous imaging data with enough sectional anatomy detail can provide a scientific basis for measuring the size of a tumor and identifying the tumor’s surgical margins in multiple dimensions using an augmented virtual reality technique.
机译:没有准确的体积测量方法来评估恶性肌肉骨骼瘤对化学疗法的反应,也没有专门的术前评估方法来评估手术切缘。分析了2012年3月至2014年3月治疗的25例恶性肌肉骨骼肿瘤。通过使用结缔切片扫描和增强虚拟现实技术,可以轻松地根据川口提出的标准准确测量肿瘤体积并确定手术切缘。标本送去进行病理检查以确定肿瘤类型。将术前手术切缘与术后手术切缘进行比较。 92%的患者在术前影像学检查的帮助下进行了根治性切除或广泛切除。仅1例因恶性肿瘤进展而进行了病灶内切除,而1例因股神经侵犯而进行了边缘切除。手术前的预测切缘与手术后的最终切缘之间无显着差异(P> 0.05)。我们的结果表明,使用具有足够的截面解剖学细节的连续成像数据可以为使用增强虚拟现实技术测量肿瘤的大小并在多个维度上识别肿瘤的手术切缘提供科学依据。

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