Comparison of nephrotoxicity of Colistin with Polymyxin B administered in currently recommended doses: a prospective study

摘要

BackgroundThe most important concern with polymyxins (Colistin and Polymyxin B) use is nephrotoxicity. There is no prospective data comparing nephrotoxicity of these two drugs, when administered in high doses and as per current recommendations. We conducted a prospective study to compare their trend of nephrotoxicity in our patient population.